Search on: COMPLEMENT C4B-BINDING PROTEIN 
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Descriptor English:   Complement C4b-Binding Protein 
Descriptor Spanish:   proteína de unión al complemento C4b 
Descriptor Portuguese:   Proteína de Ligação ao Complemento C4b 
Synonyms English:   C4b Binding Protein
C4b C3b Inactivator Cofactor
C4b-Binding Protein
C4b-Binding Protein, Complement
C4b-C3b Inactivator Cofactor
C4bC3bINA Cofactor
C4bC3bINA-Cofactor
Cofactor, C4b-C3b Inactivator
Complement 4b Binding Protein
Complement C3b C4b Inactivator Cofactor
Complement C3b-C4b Inactivator Cofactor
Complement C4b Binding Protein
Complement Component 4b Binding Protein
Complement Component 4b-Binding Protein
Protein, C4b-Binding
Protein, Complement C4b-Binding  
Tree Number:   D12.776.124.486.274.920.662
Definition English:   A serum protein that regulates the CLASSICAL COMPLEMENT ACTIVATION PATHWAY. It binds as a cofactor to COMPLEMENT FACTOR I which then hydrolyzes the COMPLEMENT C4B in the CLASSICAL PATHWAY C3 CONVERTASE (C4bC2a). 
Pharmacological Action:   Complement Inactivating Agents
 
History Note English:   2006 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   50837 
Unique Identifier:   D050716 

Occurrence in VHL:
 

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DeCS